Bi-Layer R&D Tablet Press

EP-200L

The Elizabeth EP-200L is a compact bi-layer rotary tablet press designed for formulation development, pilot-scale production, and small-batch manufacturing of layered tablets. Built with GMP-compliant materials and separated tableting and mechanical zones, it provides controlled, repeatable compression in a development-focused footprint.
19,800/hr Max Output
9, 11, or 5x5 Stations
50 kN Main Pressure

Configured for D, B, or combination multi-tooling, the EP-200L supports output up to 19,800 tablets per hour depending on tooling selection. Independent first and second layer filling, tamping, and compression allow precise control over weight, thickness, and bonding strength between layers.

Equipped with a touch screen control interface, load cells for compression monitoring, and force or gravity feeding systems, the EP-200L delivers accurate bi-layer tablet production for R&D teams and manufacturers preparing for scale-up.

Advanced Bi-Layer Compression

The Elizabeth EP-200L is designed for formulation development, clinical batches, and pilot-scale production of bi-layer tablets. As a single rotary, double-layer tablet press, it allows manufacturers to independently control the first and second layer filling, tamping, and compression stages, supporting precise weight management and strong interlayer bonding.

With multiple turret configurations available in D, B, or combination tooling, the EP-200L delivers output up to 19,800 tablets per hour depending on configuration. The machine provides 10 kN tamping force and up to 50 kN main compression force, enabling controlled consolidation of each layer before final compression. Adjustable upper punch penetration for both layers allows fine tuning of tablet density, thickness, and mechanical strength.

The EP-200L features GMP-compliant construction with separated tableting and mechanical zones to support cleanability and maintenance. A touch screen control interface with load cells for compression monitoring provides real-time visibility of pre and main compression forces. Depending on configuration, the press can be equipped with gravity or force feeding systems to ensure consistent material flow for each layer.

For organizations developing layered formulations, combination-release tablets, or specialty dual-ingredient products, the EP-200L provides the control, flexibility, and mechanical stability required at the development and pilot stage.

Main Features and Benefits

Engineered to provide maximum flexibility and precision for bi-layer formulation development.
Single Rotary Bi-Layer Compression Design

Enables independent compression of two layers for controlled weight, thickness, and interlayer bonding.

Independent Layer Filling and Tamping

Allows precise adjustment of first and second layer parameters to support complex or combination formulations.

Up to 19,800 Tablets per Hour

Supports pilot-scale and small-batch bi-layer production depending on tooling configuration.

Multiple Tooling Configurations

Available in D, B, or Combination tooling. Provides flexibility for different tablet diameters and development requirements.

10 kN Tamping and 50 kN Main Compression

Delivers controlled consolidation of each layer before final compression.

GMP-Compliant Construction

Supports pharmaceutical and nutraceutical manufacturing standards through cleanable design and separated zones.

Touch Screen Interface & Load Cells

Provides real-time visibility of compression forces and process parameters.

Force or Gravity Feeding Options

Ensures consistent material flow for each layer depending on product characteristics.

Upper Punch Overload Protection System

Helps prevent tooling damage during compression adjustments.

Reinforced Frame and Direct Turret Drive

Minimize vibration and supports stable compression performance during development work.

Technical Specifications

Mechanical Specifications
Model EP-200L
Type Single Rotary Bi-Layer Tablet Press
Number of Stations 9 (D) / 11 (B) / 5 x 5 (B/D Combination)
Turret Speed 5 – 30 RPM
Tamping Force (Pre-Compression) 10 kN
Main Compression Force (Max.) 50 kN
Machine Frame Reinforced Steel Plate Frame
Height with Hopper Approx. 1338 mm
Power 3 HP, 3 Phase, 220V / 60Hz
Electrical Specifications
Main Motor Power 3 HP
Power Supply 220V, 3 Phase, 60 Hz
Drive System Direct Turret Drive with High-Torque Reduction Gearbox
Compression Roll Load Cells Standard (Pre & Main)
Control System PC / PLC-Based Control with Touch Screen Interface
Feeder Drive AC Variable Frequency Drive (Configuration Dependent)
Tooling Specifications
Tooling Options D / B / Combination B-D (EURO / IPT)
Maximum Output (D Tooling) Up to 16,200 tablets/hour
Maximum Output (B Tooling) Up to 19,800 tablets/hour
Maximum Output (B/D Combo) Up to 6,000 tablets/hour
Maximum Tablet Diameter (D) 22 mm
Maximum Tablet Diameter (B) 16 mm
Maximum Depth of Fill (D) 18 mm
Maximum Depth of Fill (B) 17 mm
Layer Control Independent First & Second Layer Filling and Compression
Controls & Safety Specifications
Control Interface Touch Screen MMI
Compression Monitoring Load Cells for Pre & Main Compression
Ejection Pressure Monitoring Optional
Tablet Counter Integrated Digital Counter
Upper Punch Overload Protection Standard
Emergency Stop Integrated Push Button

Ready to Develop Your Bi-Layer Formulation?

If you are developing combination-release tablets, dual-ingredient products, or layered formulations, the EP-200L provides the control and flexibility required at the R&D and pilot stage. Independent layer control, real-time compression monitoring, and flexible tooling options allow you to refine each layer before scaling to full production.

Whether you are validating a new formulation or preparing for commercial transfer, the EP-200L helps bridge development and manufacturing with consistent, repeatable bi-layer compression.

Contact Elizabeth to review your layer specifications, tooling configuration, and development goals. Our team will help determine if the EP-200L is the right fit for your application.

EP-200 L
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